Document Detail

Allergic contact dermatitis due to a biocide containing 5-chloro-2-methyl-4-isothiazolin-3-one.
MedLine Citation:
PMID:  2941217     Owner:  NLM     Status:  MEDLINE    
3 cases of contact allergy due to the biocides 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one are reported. 2 workers exposed to a soluble oil containing these 2 biocides experienced allergic contact dermatitis from them. The 3rd case was that of the chemist who separated the 2 materials for the execution of this investigation. These compounds are chemically related to the biologically active components of Ectimar, Skane M-8 and Proxel CRL. Further instances of contact allergy due to these and related compounds are likely because of the apparently increasing use of such substances as antimicrobial agents in various commercial products.
C Pilger; J R Nethercott; F Weksberg
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Contact dermatitis     Volume:  14     ISSN:  0105-1873     ISO Abbreviation:  Contact Derm.     Publication Date:  1986 Apr 
Date Detail:
Created Date:  1986-08-04     Completed Date:  1986-08-04     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7604950     Medline TA:  Contact Dermatitis     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  201-4     Citation Subset:  IM    
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MeSH Terms
Dermatitis, Contact / etiology*
Dermatitis, Occupational / chemically induced*
Disinfectants / adverse effects*
Hand Dermatoses / chemically induced
Oils / adverse effects*
Patch Tests
Thiazoles / adverse effects*
Reg. No./Substance:
0/Disinfectants; 0/Oils; 0/Thiazoles; 26172-55-4/5-chloro-2-methyl-4-isothiazolin-3-one; 2682-20-4/2-methyl-4-isothiazolin-3-one

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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