Document Detail

Allergic bronchopulmonary aspergillosis in infants.
MedLine Citation:
PMID:  910766     Owner:  NLM     Status:  MEDLINE    
Allergic bronchopulmonary aspergillosis (ABPA), a serious complication of asthma, is thought to rarely afflict infants. We report three children less than 2 years of age in whom this disorder developed. The major criteria for the diagnosis include: (1) asthma, (2) recurrent pulmonary infiltrations with peripheral eosinophilia, (3) positive aspergillus skin tests at 15 minutes and at 4 to 6 hours, (4) serum precipitating antibodies to aspergillus, and (5) elevated serum IgE levels. Early diagnosis and treatment of ABPA in infants may prevent the ravages of the disease and help to sharpen our concepts of the course and immunopathogenesis.
S A Imbeau; M Cohen; C E Reed
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  American journal of diseases of children (1960)     Volume:  131     ISSN:  0002-922X     ISO Abbreviation:  Am. J. Dis. Child.     Publication Date:  1977 Oct 
Date Detail:
Created Date:  1977-11-30     Completed Date:  1977-11-30     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0370471     Medline TA:  Am J Dis Child     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1127-30     Citation Subset:  AIM; IM    
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MeSH Terms
Aspergillosis* / drug therapy,  radiography
Asthma / complications*
Bronchial Diseases / drug therapy,  etiology*,  radiography
Lung / radiography
Lung Diseases, Fungal / drug therapy,  etiology*,  radiography
Prednisone / therapeutic use
Reg. No./Substance:

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