Document Detail

Allergen-induced late asthmatic responses and increased airway responsiveness.
MedLine Citation:
PMID:  1577259     Owner:  NLM     Status:  MEDLINE    
Our understanding of the airway response to inhaled allergens has increased substantially over the past several years. In addition to the long-recognized immediate or early asthmatic response, allergens also cause late asthmatic responses and allergen-induced increase in airway responsiveness to nonsensitizing stimuli such as exercise, cold air, histamine, and methacholine. These late sequelae are most likely due to airway inflammation and appear to be more clinically relevant than is the early response in the pathogenesis of clinical atopic allergic asthma.
D W Cockcroft
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Allergy proceedings : the official journal of regional and state allergy societies     Volume:  13     ISSN:  1046-9354     ISO Abbreviation:  Allergy Proc     Publication Date:    1992 Jan-Feb
Date Detail:
Created Date:  1992-06-08     Completed Date:  1992-06-08     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  8902396     Medline TA:  Allergy Proc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1-2     Citation Subset:  IM    
Royal University Hospital, Saskatoon, Saskatchewan, Canada.
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MeSH Terms
Allergens / immunology*
Asthma / immunology,  physiopathology*
Bronchial Hyperreactivity / etiology,  physiopathology*
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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