| Allelic variants of DYX1C1 are not associated with dyslexia in India. | |
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MedLine Citation:
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PMID: 20300304 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Dyslexia is a hereditary neurological disorder that manifests as an unexpected difficulty in learning to read despite adequate intelligence, education, and normal senses. The prevalence of dyslexia ranges from 3 to 15% of the school aged children. Many genetic studies indicated that loci on 6p21.3, 15q15-21, and 18p11.2 have been identified as promising candidate gene regions for dyslexia. Recently, it has been suggested that allelic variants of gene, DYX1C1 influence dyslexia. In the present study, exon 2 and 10 of DYX1C1 has been analyzed to verify whether these single nucleotide polymorphisms (SNPs) influence dyslexia, in our population. Our study identified 4 SNPs however, none of these SNPS were found to be significantly associated with dyslexia suggesting DYX1C1 allelic variants are not associated with dyslexia. |
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Authors:
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Pushpa Saviour; Satish Kumar; U Kiran; Rajasekhara Reddy Ravuri; V R Rao; Nallur Basappa Ramachandra |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Indian journal of human genetics Volume: 14 ISSN: 0971-6866 ISO Abbreviation: Indian J Hum Genet Publication Date: 2008 Sep |
Date Detail:
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Created Date: 2010-03-19 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101223637 Medline TA: Indian J Hum Genet Country: India |
Other Details:
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Languages: eng Pagination: 99-102 Citation Subset: - |
Affiliation:
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Human Genetics Laboratory, Department of Studies in Zoology, University of Mysore, Manasagangothri, Mysore-570 006, India. |
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