Document Detail


Allan-Herndon-Dudley syndrome.
MedLine Citation:
PMID:  18589880     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Allan-Herndon-Dudley Syndrome (AHDS) is a rare X-linked disorder caused by mutation in the gene encoding the monocarboxylate transporter-8. Abnormal transport function is reflected by elevated free T3 and decreased free T4 levels along with clinical features characterized by neurological abnormalities including global developmental delay, central hypotonia, rotatory nystagmus, impaired hearing, spasticity and contractures of joints. We report a child with classical clinical features along with confirmatory deranged thyroid levels in blood.
Authors:
Sanjay Verma
Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Indian journal of pediatrics     Volume:  75     ISSN:  0973-7693     ISO Abbreviation:  Indian J Pediatr     Publication Date:  2008 Apr 
Date Detail:
Created Date:  2008-06-27     Completed Date:  2008-08-22     Revised Date:  2009-07-15    
Medline Journal Info:
Nlm Unique ID:  0417442     Medline TA:  Indian J Pediatr     Country:  India    
Other Details:
Languages:  eng     Pagination:  402-4     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, University College of Medical Science and Guru Teg Bahadur Hospital, Delhi, India. Sanjay6verma@yahoo.com
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Multiple / diagnosis*
Child
Developmental Disabilities / diagnosis
Humans
Male
Mental Retardation, X-Linked / diagnosis*
Monocarboxylic Acid Transporters / genetics*
Muscle Hypotonia / genetics,  physiopathology
Prognosis
Syndrome
Thyroid Hormones / metabolism*
Chemical
Reg. No./Substance:
0/Monocarboxylic Acid Transporters; 0/Thyroid Hormones

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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