Document Detail


All-phase MR angiography using independent component analysis of dynamic contrast enhanced MRI time series: phi-MRA.
MedLine Citation:
PMID:  16210816     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Dynamic contrast enhanced magnetic resonance imaging (dynamic MRI) represents a MRI version of non-diffusible tracer methods, the main clinical use of which is the physiological construction of what is conventionally referred to as perfusion images. The raw data utilized for constructing MRI perfusion images are time series of pixel signal alterations associated with the passage of a gadolinium containing contrast agent. Such time series are highly compatible with independent component analysis (ICA), a novel statistical signal processing technique capable of effectively separating a single mixture of multiple signals into their original independent source signals (blind separation). Accordingly, we applied ICA to dynamic MRI time series. The technique was found to be powerful, allowing for hitherto unobtainable assessment of regional cerebral hemodynamics in vivo.
Authors:
Kiyotaka Suzuki; Hitoshi Matsuzawa; Hironaka Igarashi; Masaki Watanabe; Naoki Nakayama; Ingrid L Kwee; Tsutomu Nakada
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.    
Journal Detail:
Title:  Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine     Volume:  2     ISSN:  1347-3182     ISO Abbreviation:  Magn Reson Med Sci     Publication Date:  2003 Apr 
Date Detail:
Created Date:  2005-10-07     Completed Date:  2005-11-10     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  101153368     Medline TA:  Magn Reson Med Sci     Country:  Japan    
Other Details:
Languages:  eng     Pagination:  23-7     Citation Subset:  IM    
Affiliation:
Center for Integrated Brain Science, Brain Research Institute, University of Niigata, Japan.
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Algorithms
Cerebral Infarction / pathology*,  physiopathology
Cerebrovascular Circulation
Contrast Media
Gadolinium DTPA / diagnostic use
Humans
Magnetic Resonance Angiography
Male
Middle Aged
Signal Processing, Computer-Assisted*
Chemical
Reg. No./Substance:
0/Contrast Media; 80529-93-7/Gadolinium DTPA

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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