Document Detail

All in the family: matrimonial mitral valve clicks.
MedLine Citation:
PMID:  7248029     Owner:  NLM     Status:  MEDLINE    
Mitral valve clicks with or without late systolic murmurs were detected in genetically unrelated marital partners of 5 families. The first family represented 2 successive nonconsanguineous marital unions with 3 generations of mitral valve clicks. The second family included 1 natural and 2 adopted children with clinical and echographic evidence of mitral valve prolapse. The third family was comprised of asymptomatic parents, both with nonejection clicks and mitral valve prolapse, whose daughter presented 3 years previously with syncope, palpitations, and combined mitral and tricuspid valve prolapse. The fourth family had 3 members with auscultatory and ultrasonic manifestations of billowing mitral valve, whereas the fourth member had "silent mitral valve prolapse." The fifth family represented a mother with auscultatory and echographic evidence of mitral valve prolapse; her 14-year-old daughter had both mitral and tricuspid valve prolapse, whereas the son had a bicuspid aortic valve. Both children were products of a prior marriage, and her husband has symptomatic mitral valve prolapse. We conclude that matrimonial mitral valve prolapse probably reflects the purported (6--10%) prevalence of this disorder in the general population. The consequences of such marital union on progeny is currently unclear and warrants future investigation.
K B Desser; S I Bokhari; A Benchimol; D Romney
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Angiology     Volume:  32     ISSN:  0003-3197     ISO Abbreviation:  Angiology     Publication Date:  1981 May 
Date Detail:
Created Date:  1981-07-09     Completed Date:  1981-07-09     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0203706     Medline TA:  Angiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  355-60     Citation Subset:  IM    
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MeSH Terms
Longitudinal Studies
Middle Aged
Mitral Valve Prolapse / epidemiology,  genetics*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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