| Alkylresorcinols as biomarkers of whole-grain wheat and rye intake: plasma concentration and intake estimated from dietary records. | |
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MedLine Citation:
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PMID: 18400704 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Alkylresorcinols (ARs), phenolic lipids exclusively present in the outer parts of wheat and rye grains, have been proposed as specific dietary biomarkers of whole-grain wheat and rye intake. OBJECTIVE: The objective was to validate plasma ARs as a biomarker of whole-grain wheat and rye intakes by studying the correlation between their plasma concentration and intake calculated from food records. DESIGN: In a randomized crossover study, 22 women and 8 men were given a defined amount of either whole-grain or refined-cereal-grain products to be included in their habitual diets for two 6-wk periods. Blood samples were collected and food intakes were recorded before and after each intervention period. RESULTS: Plasma AR concentrations were significantly higher after the whole-grain diet period than after the refined-grain period (P < 0.0001) and were well correlated with average daily AR intake estimated by self-reported weighed food records (Spearman's r = 0.58, P < 0.001). CONCLUSION: Plasma AR concentrations are correlated with intake assessed by food records, which suggests that ARs are selective nutritional biomarkers for the intake of whole-grain wheat and rye. |
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Authors:
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Rikard Landberg; Afaf Kamal-Eldin; Agneta Andersson; Bengt Vessby; Per Aman |
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Publication Detail:
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Type: Journal Article; Randomized Controlled Trial |
Journal Detail:
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Title: The American journal of clinical nutrition Volume: 87 ISSN: 1938-3207 ISO Abbreviation: Am. J. Clin. Nutr. Publication Date: 2008 Apr |
Date Detail:
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Created Date: 2008-04-10 Completed Date: 2008-04-28 Revised Date: 2009-05-15 |
Medline Journal Info:
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Nlm Unique ID: 0376027 Medline TA: Am J Clin Nutr Country: United States |
Other Details:
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Languages: eng Pagination: 832-8 Citation Subset: AIM; IM |
Affiliation:
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Department of Food Science, Swedish University of Agriculture Science, Uppsala, Sweden. rikard.landberg@lmv.slu.se |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Biological Markers
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blood Cross-Over Studies Diet* Diet Records Dietary Fiber / administration & dosage Female Food Habits Humans Male Middle Aged Patient Compliance Resorcinols / administration & dosage*, blood* Secale cereale* / chemistry Statistics, Nonparametric Triticum* / chemistry |
| Chemical | |
Reg. No./Substance:
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0/Biological Markers; 0/Resorcinols |
| Comments/Corrections | |
Comment In:
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Am J Clin Nutr. 2008 Apr;87(4):797-8
[PMID:
18400698
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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