Document Detail

Alkaline encrusted pyelitis.
MedLine Citation:
PMID:  16502598     Owner:  NLM     Status:  MEDLINE    
Alkaline encrusted pyelitis is an infectious disease characterised by encrustations in the wall of the upper urinary tract, surrounded by severe inflammation. Destruction of native kidneys and kidney grafts may occur, resulting in end stage renal failure. Corynebacterium group D2, an urea splitting microorganism, is nearly exclusively associated with this disease. The most important predisposing factors are previous urological procedures and an immunosuppressed state. In a suggestive clinical context, diagnosis should be made with unenhanced computed tomography findings and bacteriologic isolation of the responsible microorganism. The treatment is threefold: appropriate antibiotic therapy, by preference with glycopeptides, acidification of urine and chemolysis, and if needed, surgical removal of encrustations. We report the case of a patient who was diagnosed with this rare condition and could escape maintenance dialysis after correct diagnosis was made and conservative treatment was started using antibiotics and combined oral and local acidification.
S Van Hooland; A K Vandooren; E Lerut; R Oyen; B Maes
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Acta clinica Belgica     Volume:  60     ISSN:  1784-3286     ISO Abbreviation:  Acta Clin Belg     Publication Date:    2005 Nov-Dec
Date Detail:
Created Date:  2006-02-28     Completed Date:  2006-04-11     Revised Date:  2014-03-18    
Medline Journal Info:
Nlm Unique ID:  0370306     Medline TA:  Acta Clin Belg     Country:  Belgium    
Other Details:
Languages:  eng     Pagination:  369-72     Citation Subset:  IM    
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MeSH Terms
Corynebacterium Infections / diagnosis*,  therapy
Pyelitis / diagnosis*,  microbiology,  therapy

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