| Aliskiren, amlodipine and hydrochlorothiazide triple combination for hypertension. | |
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MedLine Citation:
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PMID: 22390800 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Cardiovascular-related morbidity and mortality is linked to hypertension with proportional gains in cardiovascular risk factor reduction with the lowering of blood pressure. Clinical trial data has shown that attaining goal blood pressure requires, for most patients, at least two antihypertensive medications, with a significant proportion requiring regimens of three or more medications. Single-pill triple combinations have returned to the market following results of increased efficacy and adherence over dual- and mono-therapy. The combination of aliskiren, amlodipine and hydrochlorothiazide is a rational choice for combination therapy and recent studies suggest that it is safe and effective in lowering blood pressure in patients who fail dual combination therapy. |
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Authors:
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Eric Judd; Edgar A Jaimes |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Expert review of cardiovascular therapy Volume: 10 ISSN: 1744-8344 ISO Abbreviation: Expert Rev Cardiovasc Ther Publication Date: 2012 Mar |
Date Detail:
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Created Date: 2012-03-06 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101182328 Medline TA: Expert Rev Cardiovasc Ther Country: England |
Other Details:
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Languages: eng Pagination: 293-303 Citation Subset: IM |
Affiliation:
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University of Alabama at Birmingham, Vascular Biology and Hypertension Program, 115 Community Health Services Building, 933 19th Street South, Birmingham, AL, USA. |
Export Citation:
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Descriptor/Qualifier:
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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