Document Detail

Alimentary factors in the development of gastric intestinal metaplasia in functional dyspeptic patients.
MedLine Citation:
PMID:  23011244     Owner:  NLM     Status:  In-Data-Review    
CONTEXT: Intestinal metaplasia of the stomach is a lesion in which metaplasia of gastric epithelial cells occurs for an intestinal phenotype. Gastric intestinal metaplasia is a lesion associated with an increase in the risk of gastric carcinoma development. Epidemiologic studies indicate a relation between dietary habits and stomach cancer development, some habits increasing the risk for it, and others have a protective effect, suggesting that antioxidants, such as vitamins A, C, and E, decrease the risk of this type of cancer. The relationship of these alimentary factors and intestinal metaplasia is unknown.
METHODS: It is a case-control, observational study in which 320 patients with functional dyspepsia, divided in two groups, were assessed. The case I group (individuals with intestinal metaplasia) had their dietary pattern compared to that of the control group, constituted of individuals similar to those in the case group but without intestinal metaplasia, through a food frequency questionnaire.
RESULTS: The analysis of the dietary pattern of functional dyspeptic patients with intestinal metaplasia, and its comparison with those without intestinal metaplasia, showed a higher frequency of canned and smoked foods consumption in the first group and, on the other hand, a higher consumption of fruits and vegetables in patients without intestinal metaplasia. No effect of salt consumption was detected.
CONCLUSIONS: The results obtained in this study suggest changes in the diet, with a decrease in the consumption of smoked and canned foods, and an increase in the consumption of fruits and vegetables, can lead to a diminution of gastric intestinal metaplasia cases.
Aline Gamarra Taborda; João Carlos Prolla
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Arquivos de gastroenterologia     Volume:  49     ISSN:  1678-4219     ISO Abbreviation:  Arq Gastroenterol     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-09-26     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  15310600R     Medline TA:  Arq Gastroenterol     Country:  Brazil    
Other Details:
Languages:  eng     Pagination:  208-13     Citation Subset:  IM    
Federal University of Rio Grande do Sul, Porto Alegre, RS, Brazil.
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