Document Detail

Alien hand syndrome: influence of neglect on the clinical presentation of frontal and callosal variants.
MedLine Citation:
PMID:  9220259     Owner:  NLM     Status:  MEDLINE    
Three patients with mesial frontal and extensive callosal lesions due to anterior cerebral artery infarction manifested an alien hand syndrome (AHS) with varied features. Patient 1 with left hemispheric lesion showed right hand's impulsive reaching and grasping and left hand's antagonistic movements to the right (intermanual conflict; IMC). Patients 2 and 3 with right hemispheric lesion manifested a left hemihypokinesia which was thought to have suppressed the frequency and amplitude or even the occurrence of left hand's reaching and grasping. IMC and other left hand's non-antagonistic, irrelevant movements to the right remained. Because the term "IMC" is often misused and not strictly defined, its association with right hand's reaching and grasping is quite uncommon, its significance as a sign of callosal disconnection is not well validated, and because left hand's reaching and grasping tend to be suppressed by motor neglect, a trend may then develop for the right hand to be the sole focus of pathological behaviour in patients with the so-called frontal AHS (Feinberg, Schindler, Flanagan et al., 1992).
J L Chan; E D Ross
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Cortex; a journal devoted to the study of the nervous system and behavior     Volume:  33     ISSN:  0010-9452     ISO Abbreviation:  Cortex     Publication Date:  1997 Jun 
Date Detail:
Created Date:  1997-08-28     Completed Date:  1997-08-28     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0100725     Medline TA:  Cortex     Country:  ITALY    
Other Details:
Languages:  eng     Pagination:  287-99     Citation Subset:  IM    
Department of Neurology, Chang Gung Memorial Hospital, Taipei, Taiwan.
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MeSH Terms
Agnosia / diagnosis,  physiopathology*,  psychology
Apraxias / diagnosis,  physiopathology,  psychology
Attention / physiology*
Awareness / physiology*
Brain Damage, Chronic / diagnosis,  physiopathology,  psychology
Brain Mapping
Cerebral Infarction / diagnosis*,  physiopathology,  psychology
Corpus Callosum / physiopathology*
Frontal Lobe / physiopathology*
Functional Laterality / physiology*
Hand / innervation
Middle Aged
Neuropsychological Tests
Psychomotor Performance / physiology

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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