| Algodystrophy in conjunction with van der Hoeve's syndrome. | |
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MedLine Citation:
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PMID: 7554566 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Van der Hoeve's syndrome is the all-round variant of Lobstein's disease (late osteogenesis imperfecta) and is characterized by the concurrent presence of osteoporosis, blue sclerae, and deafness. The literature has reported sporadic cases of a combination of algodystrophic syndrome and Lobstein's disease. Our case represents a classic example: a 50-year-old woman with blue sclerae since birth, bilateral deafness, major dental alterations, vitreous osteoporosis and a history of pathological fractures who, two years from the onset of menopause, complained of pain involving the right ankle. After admission to our Department, a diagnosis of algodystrophy combined with van der Hoeve's syndrome was made on the basis of her clinical history, objective signs and x-ray results. Treatment consisted of i.v. clodronate disodium at a dose of 300 mg daily in 250 ml saline solution for 7 consecutive days. At the end of the treatment cycle the patient reported an improvement in her symptoms with nearly total regression of right ankle pain, while swelling disappeared within a few weeks. |
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Authors:
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G Chérié-Lignière; U Tamborini; P Grosso |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Clinical and experimental rheumatology Volume: 13 ISSN: 0392-856X ISO Abbreviation: Clin. Exp. Rheumatol. Publication Date: 1995 May-Jun |
Date Detail:
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Created Date: 1995-11-13 Completed Date: 1995-11-13 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8308521 Medline TA: Clin Exp Rheumatol Country: ITALY |
Other Details:
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Languages: eng Pagination: 361-5 Citation Subset: IM |
Affiliation:
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Department of Systemic and Local Treatment of Chronic Inflammatory Rheumatism, G. Pini Orthopaedics Institute, Milan, Italy. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Clodronic Acid
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administration & dosage Female Humans Infusions, Intravenous Middle Aged Osteogenesis Imperfecta / complications*, drug therapy Reflex Sympathetic Dystrophy / complications*, drug therapy |
| Chemical | |
Reg. No./Substance:
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10596-23-3/Clodronic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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