| Alfred Blalock and thymectomy for myasthenia gravis. | |
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MedLine Citation:
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PMID: 3548618 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In 1936, Alfred Blalock performed the successful removal of a thymic tumor in a patient with myasthenia gravis. The patient experienced marked and sustained improvement for several years. Blalock prophesized then that exploration of the thymic region would be indicated in all patients with severe myasthenia gravis. A few years later, in 1941, he applied this theory by introducing thymectomy for nonthymomatous myasthenia and achieved similar improvement. Despite modern sophisticated knowledge about the disease and advances in thoracic surgical techniques, Blalock's original observations remain valid, and thymectomy has become a standard treatment for myasthenia gravis the world over. |
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Authors:
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P A Kirschner |
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Publication Detail:
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Type: Biography; Historical Article; Journal Article |
Journal Detail:
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Title: The Annals of thoracic surgery Volume: 43 ISSN: 0003-4975 ISO Abbreviation: Ann. Thorac. Surg. Publication Date: 1987 Mar |
Date Detail:
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Created Date: 1987-04-08 Completed Date: 1987-04-08 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 15030100R Medline TA: Ann Thorac Surg Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 348-9 Citation Subset: AIM; IM; Q |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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History, 20th Century Humans Myasthenia Gravis / history*, surgery Thymectomy / history*, methods United States |
| Personal Name Subject | |
Personal Name Subject:
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A Blalock |
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