| Aldosterone-producing tumors (Conn's syndrome). | |
| | |
MedLine Citation:
|
PMID: 2180043 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Adenomas of the adrenal cortex which produce aldosterone (APA) are among the surgically correctible causes of hypertension accounting for 0.5 to 1.0% of all hypertensive etiologies. The adenomas have a 5:1 predilection for women and generally present with hypertension or profound hypokalemia. A low plasma renin activity completes the triad for primary hyperaldosteronism which could be caused by adrenocortical cancer, a neoplasm with an average diameter of 12 cm, or idiopathic hyperaldosteronism (IHA), a bilateral hyperplasia of the zona glomerulosa of the adrenal cortex which responds poorly to surgical resection. The adenomas are small (2 cm) but can be localized by imaging or selective venous sampling. Resection has a high success rate with minimal morbidity. |
| | |
Authors:
|
R C Merrell |
Related Documents
:
|
1362543 - Neurohormonal consequences of diuretics in different cardiovascular syndromes. 20027193 - Aldosterone and arterial hypertension. 4071363 - Evaluation and management of childhood hypertension. |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Seminars in surgical oncology Volume: 6 ISSN: 8756-0437 ISO Abbreviation: Semin Surg Oncol Publication Date: 1990 |
Date Detail:
|
Created Date: 1990-04-26 Completed Date: 1990-04-26 Revised Date: 2005-11-16 |
Medline Journal Info:
|
Nlm Unique ID: 8503713 Medline TA: Semin Surg Oncol Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 66-70 Citation Subset: IM |
Affiliation:
|
Department of Surgery, University of Texas M.D. Anderson Cancer Center, Houston 77030. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adenoma
/
complications*,
metabolism Adrenal Cortex Neoplasms / complications*, metabolism Adult Aldosterone / biosynthesis* Female Humans Hyperaldosteronism / etiology* Male Middle Aged |
| Chemical | |
Reg. No./Substance:
|
52-39-1/Aldosterone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: APUD update.
Next Document: Hormonal therapy for prostate cancer.