| Aldosterone as an independent factor in cerebrovascular damage. | |
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MedLine Citation:
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PMID: 19021028 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Aldosterone is produced not only in the adrenal gland but also in other tissues, including the brain, where it plays an important role in the control of blood pressure and water and electrolyte homeostasis. Aldosterone has also been demonstrated to be a major factor in target organ damage independent of its effects on blood pressure. Herein we review the pathophysiology of aldosterone action in the brain and the clinical and experimental studies on the detrimental effects of aldosterone in the brain. |
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Authors:
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Paolo Mulatero; Mimma Caserta; Chiara Bertello; Domenica Schiavone; Andrea Verhovez; Giuseppe Giraudo; Fulvio Morello; Franco Veglio |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't; Review |
Journal Detail:
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Title: Clinical and experimental hypertension (New York, N.Y. : 1993) Volume: 30 ISSN: 1525-6006 ISO Abbreviation: Clin. Exp. Hypertens. Publication Date: 2008 Nov |
Date Detail:
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Created Date: 2008-11-21 Completed Date: 2009-02-06 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9305929 Medline TA: Clin Exp Hypertens Country: United States |
Other Details:
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Languages: eng Pagination: 785-97 Citation Subset: IM |
Affiliation:
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Division of Internal Medicine and Hypertension, Department of Medicine and Experimental Oncology, University of Torino, Torino, Italy. paolo.mulatero@libero.it |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aldosterone
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adverse effects,
physiology* Animals Blood Pressure / physiology Cerebrovascular Disorders / etiology, physiopathology* Disease Models, Animal Humans Hypertension / complications, physiopathology* Risk Factors Stroke / etiology, physiopathology |
| Chemical | |
Reg. No./Substance:
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52-39-1/Aldosterone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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