| Aldolase and adenosine deaminase activity in lymphocytes of patients with glomerulonephritis. | |
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MedLine Citation:
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PMID: 6654634 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Studies on the adenosine deaminase (ADA) and aldolase activities in lymphocytes were performed in 67 patients with glomerulonephritis (gn) and in 20 healthy individuals from the control group to get an insight into the lymphocyte metabolism. Statistically significant decrease of ADA activity was found in the groups of patients with chronic proliferative gn, membranoproliferative gn, membranous gn and lupus nephritis in comparison with the healthy individuals from the control group. As far as decrease of aldolase activity is concerned it has reached statistical significance in patients with mesangial gn, membranoproliferative gn, membranous gn and lupus nephritis. The lymphocyte metabolism did not show any abnormalities in the enzymatic indicators only in patients with acute proliferative gn and submicroscopic gn. The activity comparison between both enzymes in the lymphocytes, contrasted on the basis of high and low clinical dynamics of gn, revealed a tendency to lower ADA and aldolase activities in patients with high clinical dynamics. However, this difference was at the limit of statistical significance (p less than or equal to 0.10). |
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Authors:
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M Klinger; Z Szewczyk; M Robak |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: International urology and nephrology Volume: 15 ISSN: 0301-1623 ISO Abbreviation: Int Urol Nephrol Publication Date: 1983 |
Date Detail:
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Created Date: 1984-02-24 Completed Date: 1984-02-24 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0262521 Medline TA: Int Urol Nephrol Country: HUNGARY |
Other Details:
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Languages: eng Pagination: 273-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenosine Deaminase
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blood* Adult Female Fructose-Bisphosphate Aldolase / blood* Glomerulonephritis / enzymology* Humans Lymphocytes / enzymology* Male Middle Aged Nucleoside Deaminases / blood* |
| Chemical | |
Reg. No./Substance:
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EC 3.5.4.-/Nucleoside Deaminases; EC 3.5.4.4/Adenosine Deaminase; EC 4.1.2.13/Fructose-Bisphosphate Aldolase |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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