Document Detail


Aldicarb food poisonings in California, 1985-1988: toxicity estimates for humans.
MedLine Citation:
PMID:  2386419     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Three outbreaks of food poisoning involving watermelons or cucumbers and caused by the carbamate pesticide aldicarb occurred in California between 1985 and 1988. For each outbreak, and for an outbreak of aldicarb poisoning associated with English cucumbers previously reported in the literature, dosages of aldicarb sulfoxide that caused the illnesses were estimated. Estimated dosages ranged between 0.0023 [corrected] and 0.06 mg/kg body weight, and most were well below the 0.025 mg/kg Lowest Observed Effect Level (LOEL) for subclinical blood cholinesterase depression previously reported for humans. These findings are consistent with aldicarb sulfoxide (ASO) illnesses that have occurred in other states. Aldicarb appears to be more toxic than previously suspected. Scientific and regulatory implications are discussed.
Authors:
L R Goldman; M Beller; R J Jackson
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of environmental health     Volume:  45     ISSN:  0003-9896     ISO Abbreviation:  Arch. Environ. Health     Publication Date:    1990 May-Jun
Date Detail:
Created Date:  1990-09-20     Completed Date:  1990-09-20     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  0212627     Medline TA:  Arch Environ Health     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  141-7     Citation Subset:  AIM; IM    
Affiliation:
California Department of Health Services, Environmental Epidemiology and Toxicology Branch, Emeryville.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Aldicarb / analogs & derivatives,  analysis,  metabolism,  poisoning*,  toxicity
California / epidemiology
Child
Disease Outbreaks*
Female
Food Contamination*
Foodborne Diseases / epidemiology*
Fruit / analysis
Humans
Insecticides / poisoning*
Male
Middle Aged
United States / epidemiology
Vegetables / analysis
Chemical
Reg. No./Substance:
0/Insecticides; 116-06-3/Aldicarb; 1646-87-3/aldicarb sulfoxide
Comments/Corrections
Erratum In:
Arch Environ Health 1990 Nov-Dec;45(6):following 380

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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