| Alcoholism and cellular vulnerability in different brain regions. | |
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MedLine Citation:
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PMID: 22292736 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Alcohol-induced damage causes dysfunction of selected brain regions. Multidisciplinary studies have provided an extensive description of changes observed in neurons and glia following alcohol consumption. In this study the authors have elucidated preferential cellular vulnerability in three different brain regions. Autopsy material of the prefrontal cortex, striatum, and substantia nigra obtained from the brain tissue of alcoholic subjects was used in this study. We found that dendritic tree and astroglial damage is irreversible, while neuronal somata and most axons do not display irreversible changes. |
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Authors:
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Sandra Skuja; Valerija Groma; Liene Smane |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Ultrastructural pathology Volume: 36 ISSN: 1521-0758 ISO Abbreviation: Ultrastruct Pathol Publication Date: 2012 |
Date Detail:
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Created Date: 2012-02-01 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8002867 Medline TA: Ultrastruct Pathol Country: England |
Other Details:
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Languages: eng Pagination: 40-7 Citation Subset: IM |
Affiliation:
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Institute of Anatomy and Anthropology, Riga Stradins University , Riga , Latvia. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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