| Alcohol use and prognosis in patients with coronary heart disease. | |
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MedLine Citation:
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PMID: 12732795 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Substantial evidence has shown that moderate drinkers have lower rates of coronary heart disease (CHD) than abstainers, but the effects of alcohol consumption among patients with established CHD are less clear. Alcohol intake has important effects on risk factors for reinfarction, including higher levels of high-density lipoprotein cholesterol and triglycerides, lower levels of fibrinogen and other prothrombotic factors, lower fibrinolytic potential, and antiplatelet activity. Studies of patients at risk for CHD, such as those with diabetes, hypertension, and hyperlipidemia, have shown that the association of moderate drinking and CHD is at least as strong as it is in the general population. Most recently, studies have found that survivors of acute myocardial infarction who drink moderately have a risk of death approximately 20%-30% lower than do abstainers or rare drinkers. Nonetheless, the risks and benefits of alcohol use remain complex, even among patients with CHD, and no simple recommendation regarding alcohol consumption can be made for all patients. |
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Authors:
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Kenneth J Mukamal |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Preventive cardiology Volume: 6 ISSN: 1520-037X ISO Abbreviation: Prev Cardiol Publication Date: 2003 |
Date Detail:
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Created Date: 2003-05-06 Completed Date: 2003-07-11 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 9813731 Medline TA: Prev Cardiol Country: United States |
Other Details:
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Languages: eng Pagination: 93-8 Citation Subset: IM |
Copyright Information:
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Copyright 2003 CHF, Inc. |
Affiliation:
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Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Libby-303, Boston, MA 02215, USA. kmukamal@caregroup.harvard.edu |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Alcohol Drinking* Coronary Disease / diagnosis*, epidemiology Ethanol / administration & dosage* Evidence-Based Medicine Humans Prognosis Risk Factors Solvents / administration & dosage* |
| Chemical | |
Reg. No./Substance:
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0/Solvents; 64-17-5/Ethanol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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