Document Detail


Alcohol-related seizures.
MedLine Citation:
PMID:  17044577     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Alcohol-related seizures are defined as adult-onset seizures that occur in the setting of chronic alcohol dependence. Alcohol withdrawal is the cause of seizures in a subgroup of these patients; however, concurrent risk factors including pre-existing epilepsy, structural brain lesions, and the use of illicit drugs contribute to the development of seizures in many patients. New onset or a new pattern of alcohol-related seizures, e.g., focal seizures or status epilepticus, should prompt a thorough diagnostic evaluation. This is not indicated if patients have previously completed a comprehensive evaluation and the pattern of current seizures is consistent with past events. Treatment is initially directed at aggressively terminating current seizure activity. This should be followed by prevention of recurrent alcohol-related seizures and progression to status epilepticus during the ensuing 6-h high-risk period. Our purpose is to present recommendations for the diagnostic evaluation, treatment and disposition of these patients based on the current literature.
Authors:
Niels K Rathlev; Andrew S Ulrich; Norman Delanty; Gail D'Onofrio
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  The Journal of emergency medicine     Volume:  31     ISSN:  0736-4679     ISO Abbreviation:  J Emerg Med     Publication Date:  2006 Aug 
Date Detail:
Created Date:  2006-10-18     Completed Date:  2006-11-07     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8412174     Medline TA:  J Emerg Med     Country:  United States    
Other Details:
Languages:  eng     Pagination:  157-63     Citation Subset:  IM    
Affiliation:
Department of Emergency Medicine, Boston Medical Center and Boston, University School of Medicine, Boston, Massachusetts 02118, USA.
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MeSH Terms
Descriptor/Qualifier:
Alcohol Withdrawal Seizures* / complications,  diagnosis,  therapy
Anticonvulsants / therapeutic use
Benzodiazepines / therapeutic use
Brain / pathology
Diagnostic Imaging
Humans
Risk Factors
Chemical
Reg. No./Substance:
0/Anticonvulsants; 12794-10-4/Benzodiazepines
Comments/Corrections
Comment In:
J Emerg Med. 2008 May;34(4):463; author reply 463   [PMID:  18206339 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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