Document Detail

Alcohol-nutrition interaction: 1984 update.
MedLine Citation:
PMID:  6399449     Owner:  NLM     Status:  MEDLINE    
Alcohol remains a prevailing cause of malnutrition resulting in a variety of deficiency states secondary to decreased intake of nutrients. In addition to various well described primary malnutrition syndromes, secondary malnutrition may result from the interaction of ethanol with nutrient digestion, absorption or utilization. Some of the latter alcohol-nutrient interactions have been recently defined and their pathogenesis is discussed in this review. Included are interactions with thiamine, folic acid, vitamin A and disorders secondary to amino acid imbalances. The rationale for various forms of therapy is reviewed, including the treatment aimed at correcting the "hypermetabolic state" in alcoholics ad the pitfalls of excess nutrient administration (particularly as it pertains to pyridoxine, vitamin A and amino acids). The desirability of recognizing early precirrhotic stages of alcoholic fibrosis is emphasized, in order to start therapy prior to the medical and/or social disintegration of the alcoholic.
C S Lieber
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Alcohol (Fayetteville, N.Y.)     Volume:  1     ISSN:  0741-8329     ISO Abbreviation:  Alcohol     Publication Date:    1984 Mar-Apr
Date Detail:
Created Date:  1985-10-03     Completed Date:  1985-10-03     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8502311     Medline TA:  Alcohol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  151-7     Citation Subset:  IM    
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MeSH Terms
Alcoholism / complications*,  diet therapy,  metabolism
Amino Acids / blood
Choline Deficiency / etiology
Liver / metabolism
Liver Diseases, Alcoholic / metabolism
Methionine / deficiency
Nutrition Disorders / etiology*
Oxygen Consumption
Tryptophan / blood
Vitamin A Deficiency / etiology
Reg. No./Substance:
0/Amino Acids; 63-68-3/Methionine; 73-22-3/Tryptophan

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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