Document Detail

Alcohol involvement as a function of co-occurring alcohol use disorders and major depressive episode: evidence from the National Epidemiologic Survey on Alcohol and Related Conditions.
MedLine Citation:
PMID:  21440383     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Co-occurring alcohol use disorder and major depression (C-ALDP) is a major public health problem. Yet, the available evidence is mixed regarding the implications of C-ALDP for alcohol involvement. The purpose of this research was to examine the associations between past 12-month co-occurring AUDs (abuse and dependence) and major depressive episode (MDE) and alcohol involvement in a representative community sample.
DESIGN: The National Epidemiologic Survey on Alcohol and Related Conditions (NESARC) is a national household survey of 43,093 adults ages 18 and older. For the NESARC, the target population is the civilian noninstitutionalized population, 18 years of age and older, living in the United States and the District of Columbia.
METHODS: All NESARC interviews were conducted with the Alcohol Use Disorder and Associated Disabilities Interview Schedule--DSM IV Version (AUDADIS-IV; Grant et al., 2003a).
RESULTS: Prevalence of past 12-month co-occurring AUD (abuse or dependence) and MDE was 1.2%, corresponding to about 2.4 million adults ages 18 and older. Among males with alcohol dependence, comorbid MDE was associated with a greater number of days drinking at home alone. Among females and males with alcohol abuse and dependence, comorbid MDE was associated with higher prevalence of drinking to enhance depressed mood. Comorbid MDE was also associated with lower levels of some drinking behaviors among those with alcohol abuse.
CONCLUSIONS: Co-occurring AUDs and MDE are associated with specific dimensions of alcohol involvement, and this association is more consistent for alcohol dependence than abuse.
James A Cranford; Susan Nolen-Hoeksema; Robert A Zucker
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Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural     Date:  2011-03-26
Journal Detail:
Title:  Drug and alcohol dependence     Volume:  117     ISSN:  1879-0046     ISO Abbreviation:  Drug Alcohol Depend     Publication Date:  2011 Sep 
Date Detail:
Created Date:  2011-08-01     Completed Date:  2012-02-06     Revised Date:  2014-09-21    
Medline Journal Info:
Nlm Unique ID:  7513587     Medline TA:  Drug Alcohol Depend     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  145-51     Citation Subset:  IM    
Copyright Information:
Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.
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MeSH Terms
Aged, 80 and over
Alcohol Drinking / epidemiology
Alcohol-Related Disorders / epidemiology*
Alcoholism / epidemiology
Central Nervous System Depressants / adverse effects
Databases, Factual
Depressive Disorder, Major / epidemiology*
District of Columbia / epidemiology
Ethanol / adverse effects
Health Surveys
Interview, Psychological
Middle Aged
Psychiatric Status Rating Scales
Public Health
Time Factors
Young Adult
Grant Support
Reg. No./Substance:
0/Central Nervous System Depressants; 3K9958V90M/Ethanol

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