| Alcohol intake over the life course and mammographic density. | |
| | |
MedLine Citation:
|
PMID: 19184416 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Alcohol intake is one of the few modifiable risk factors for breast cancer. Current alcohol intake has been associated with mammographic density, a strong intermediate marker of breast cancer risk, though few studies have examined the effect of both current and average lifetime alcohol intake. We interviewed 262 participants from a New York birth cohort (born 1959-1963) and obtained mammograms from 163 (71.5% of participants with a mammogram). We collected information on alcohol intake by beverage type separately for each decade of life. We used multivariable linear models to assess the associations between current and average lifetime alcohol intake and mammographic density using a quantitative measure of density from digitized images. Overall, current alcohol intake was more strongly associated with mammographic density than average lifetime alcohol intake; compared with nondrinkers, those with current intake of seven or more servings per week had on average 12.3% (95% CI: 4.3, 20.4) higher density, adjusted for average lifetime alcohol intake, age, and body mass index. We observed a consistent inverse association for red wine intake and mammographic density, suggesting that the positive association between mammographic density and overall alcohol intake was driven by other types of alcoholic beverages. Our findings support an association between current alcohol intake and increased mammographic density independent of the effect of average lifetime alcohol intake. If replicated, our study suggests that reducing current alcohol consumption, particularly beer and white wine intake, may be a means of reducing mammographic density regardless of intake earlier in life. |
| | |
Authors:
|
Julie D Flom; Jennifer S Ferris; Parisa Tehranifar; Mary Beth Terry |
Related Documents
:
|
16433736 - Alcohol prices, beverage quality, and the demand for alcohol: quality substitutions and... 1156066 - Alcohol and dietary factors in cirrhosis. an epidemiological study of 304 alcoholic pat... 16812306 - Dynamic effects of food magnitude on interim-terminal interaction. 2943026 - Knowledge, attitudes and behaviour in relation to diarrhoea in a rural community in burma. 11141296 - Monitoring of domestic and imported eggs for veterinary drug residues by the canadian f... 1303036 - The state of food hygiene and foodborne diseases: requirements for the future. |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. Date: 2009-01-29 |
Journal Detail:
|
Title: Breast cancer research and treatment Volume: 117 ISSN: 1573-7217 ISO Abbreviation: Breast Cancer Res. Treat. Publication Date: 2009 Oct |
Date Detail:
|
Created Date: 2009-09-17 Completed Date: 2009-12-16 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 8111104 Medline TA: Breast Cancer Res Treat Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 643-51 Citation Subset: IM |
Affiliation:
|
Department of Epidemiology, Columbia University, Mailman School of Public Health, 722 West 168th Street, Room 731, New York, NY 10032, USA. jf2259@columbia.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Alcohol Drinking / adverse effects* Alcoholic Beverages / adverse effects Breast Neoplasms / radiography* Female Humans Mammography Middle Aged Questionnaires Risk Factors Time Young Adult |
| Grant Support | |
ID/Acronym/Agency:
|
K07CA90685/CA/NCI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Stimulation of the bradykinin B(1) receptor induces the proliferation of estrogen-sensitive breast c...
Next Document: Detection and characterization of a sialoglycosylated bacterial ABC-type phosphate transporter prote...