| Alcohol and the developing brain: neuroanatomical studies. | |
| | |
MedLine Citation:
|
PMID: 15303628 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
One of the distinguishing features of prenatal alcohol exposure is impaired cognitive and behavioral function resulting from damage to the central nervous system. Information available from the small number of autopsied cases in humans indicates that the offspring of mothers who abused alcohol during pregnancy have various neuroanatomical alterations ranging from gross reductions in brain size to cellular alterations. Recent neuroimaging technology provides the most powerful tool for assessing the neurotoxic effects of fetal alcohol exposure in living organisms and for exploring the relationship between behavioral dysfunction and brain damage at the regional level. Recently, animal research has suggested that the damaging effects of alcohol exposure during brain development could be prevented or attenuated by various pharmacological manipulations or by complex motor training. These promising findings provide directions for developing future prevention or intervention strategies. |
| | |
Authors:
|
Wei-Jung A Chen; Susan E Maier; Scott E Parnell; James R West |
Related Documents
:
|
17984398 - Causal inferences regarding prenatal alcohol exposure and childhood externalizing probl... 3335868 - Residential mobility during pregnancy: implications for environmental teratogenesis. 12893478 - Children with fetal alcohol syndrome in north dakota: a case control study utilizing bi... 12676628 - Methyl mercury and inorganic mercury in swedish pregnant women and in cord blood: influ... 8237918 - The north american collaborative study of maternal phenylketonuria. status report 1993. 20015328 - Circulating and decidual th17 cell levels in healthy pregnancy. |
Publication Detail:
|
Type: Journal Article; Review |
Journal Detail:
|
Title: Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism Volume: 27 ISSN: 1535-7414 ISO Abbreviation: Alcohol Res Health Publication Date: 2003 |
Date Detail:
|
Created Date: 2004-08-11 Completed Date: 2004-08-26 Revised Date: 2005-11-16 |
Medline Journal Info:
|
Nlm Unique ID: 100900708 Medline TA: Alcohol Res Health Country: United States |
Other Details:
|
Languages: eng Pagination: 174-80 Citation Subset: IM |
Affiliation:
|
Department of Human Anatomy and Medical Neurobiology, College of Medicine, Texas A&M University System Health Science Center, College Station, Texas, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Brain / anatomy & histology*, drug effects*, growth & development Diagnostic Imaging / methods Ethanol / adverse effects* Female Humans Pregnancy Prenatal Exposure Delayed Effects* |
| Chemical | |
Reg. No./Substance:
|
64-17-5/Ethanol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Positron emission tomography--a tool for identifying the effects of alcohol dependence on the brain.
Next Document: Male and female sensitivity to alcohol-induced brain damage.