Document Detail

Alcohol counselling of 85 pregnant problem drinkers: effect on drinking and fetal outcome.
MedLine Citation:
PMID:  3370196     Owner:  NLM     Status:  MEDLINE    
Eighty-five pregnant problem drinkers were given intensive counselling throughout gestation to persuade them to reduce or stop their alcohol intake. Nevertheless, 7% of their blood specimens collected at follow-up visits contained ethanol. Fifty-five women (65%) were able to reduce their alcohol consumption by at least 50%. Alcohol abuse was associated in a dose-dependent manner with fetal growth retardation detectable by ultrasonography from 27 weeks gestation. Twenty infants (24%) had a complete fetal alcohol syndrome and 22 (26%) had some features of 'fetal alcohol effects' (FAE). In addition, the rate of structural malformations was high (13%). Of the women with continuous alcohol abuse 89% gave birth to infants with at least one feature of FAE compared with only 40% of those who decreased their alcohol consumption.
E Halmesmäki
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  British journal of obstetrics and gynaecology     Volume:  95     ISSN:  0306-5456     ISO Abbreviation:  Br J Obstet Gynaecol     Publication Date:  1988 Mar 
Date Detail:
Created Date:  1988-06-24     Completed Date:  1988-06-24     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  7503752     Medline TA:  Br J Obstet Gynaecol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  243-7     Citation Subset:  AIM; IM    
Department of Obstetrics and Gynaecology, University Central Hospital, Helsinki, Finland.
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MeSH Terms
Alcoholism / complications,  therapy*
Congenital Abnormalities / etiology
Fetal Alcohol Syndrome / diagnosis
Fetal Growth Retardation / etiology
Infant, Newborn
Pregnancy Complications / therapy*
Prenatal Care*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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