Document Detail


Alcohol consumption during pregnancy and its effects on neurodevelopment: what is known and what remains uncertain.
MedLine Citation:
PMID:  19215606     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
It has been claimed that mothers' drinking during pregnancy may affect the neurodevelopment of around 1% of all children. If this is true, then prenatal alcohol exposure represents an important risk factor for neurodevelopmental problems, giving rise to a large burden of disability which could be potentially preventable. Evidence to support this idea has come from animal experiments and human observational studies. However, such findings need to be supported by more robust research designs. Because randomized controlled trials in this area are neither feasible nor ethical, suggestions are made for further research making more use of natural experiments.
Authors:
Ron Gray; Raja A S Mukherjee; Michael Rutter
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Publication Detail:
Type:  Comment; Journal Article     Date:  2009-02-10
Journal Detail:
Title:  Addiction (Abingdon, England)     Volume:  104     ISSN:  1360-0443     ISO Abbreviation:  Addiction     Publication Date:  2009 Aug 
Date Detail:
Created Date:  2009-07-23     Completed Date:  2010-01-27     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9304118     Medline TA:  Addiction     Country:  England    
Other Details:
Languages:  eng     Pagination:  1270-3     Citation Subset:  IM    
Affiliation:
National Perinatal Epidemiology Unit, University of Oxford, Headington, Oxford, UK. ron.gray@npeu.ox.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Alcohol Drinking / adverse effects*,  epidemiology
Child Behavior Disorders / epidemiology,  etiology*,  prevention & control
Child Development
Cognition Disorders / epidemiology,  etiology*,  prevention & control
Evidence-Based Medicine
Female
Fetal Alcohol Syndrome / epidemiology,  etiology*,  prevention & control
Humans
Infant, Newborn
Maternal Behavior
Mothers
Pregnancy
Prenatal Exposure Delayed Effects / epidemiology,  etiology*,  prevention & control
Comments/Corrections
Comment On:
Addiction. 2009 Aug;104(8):1275-6; discussion 1279-80   [PMID:  19624317 ]
Comment In:
Addiction. 2009 Aug;104(8):1276-8; discussion 1279-80   [PMID:  19624318 ]
Addiction. 2009 Aug;104(8):1278-9; discussion 1279-80   [PMID:  19624319 ]
Addiction. 2009 Aug;104(8):1274-5; discussion 1279-80   [PMID:  19624316 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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