Document Detail


Alcohol consumption as a risk factor for pneumonia: a systematic review and meta-analysis.
MedLine Citation:
PMID:  20380771     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The aim of this study was to quantify the association between alcohol consumption and incidence of pneumonia and to examine possible pathways. This was done by a systematic review and meta-analyses on the dose-response relationship between alcohol consumption or alcohol-use disorders and the incidence of community-acquired pneumonia (CAP). The relative risk (RR) of CAP increased monotonically with increasing alcohol consumption. Individuals consuming 24, 60, and 120 g of pure alcohol daily demonstrated RRs for incident CAP of 1·12 (95% CI 1·02-1·23), 1·33 (95% CI 1·06-1·67) and 1·76 (95% CI 1·13-2·77), respectively, relative to non-drinkers. Clinically defined alcohol-use disorders were associated with an eightfold increased risk of CAP (RR 8·22, 95% CI 4·85-13·95). In conclusion, alcohol was found to be a risk factor for pneumonia with a clear statistical association, and a monotonic dose-response relationship.
Authors:
A V Samokhvalov; H M Irving; J Rehm
Publication Detail:
Type:  Journal Article; Meta-Analysis; Research Support, N.I.H., Extramural; Review     Date:  2010-04-12
Journal Detail:
Title:  Epidemiology and infection     Volume:  138     ISSN:  1469-4409     ISO Abbreviation:  Epidemiol. Infect.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-10-25     Completed Date:  2010-11-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8703737     Medline TA:  Epidemiol Infect     Country:  England    
Other Details:
Languages:  eng     Pagination:  1789-95     Citation Subset:  IM    
Affiliation:
Public Health and Regulatory Policy, Centre for Addiction and Mental Health, Toronto, Ontario, Canada. avsamokhvalov@yahoo.ca
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MeSH Terms
Descriptor/Qualifier:
Alcohol Drinking / adverse effects*
Community-Acquired Infections / epidemiology
Female
Humans
Incidence
Male
Pneumonia / epidemiology*
Risk Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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