| Alcohol consumption and aortic arch calcification in an older Chinese sample: The Guangzhou Biobank Cohort Study. | |
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MedLine Citation:
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PMID: 21813196 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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OBJECTIVE: To examine the association between alcohol consumption and aortic arch calcification (AAC) in an older Chinese sample. METHODS: In 27,844 older people aged 50-85, socioeconomic position and lifestyle factors were assessed by a questionnaire. The presence and severity of AAC were diagnosed from chest X-ray by two experienced radiologists. RESULTS: In men, the risk for AAC increased significantly in frequent or excessive drinkers [adjusted odds ratio (OR)=1.36 (95% confidence interval (CI) 1.16-1.59) and 1.49 (1.21-1.83) for those who drank >5times/week and those who drank excessively, respectively] (P for trend from 0.002 to 0.001). When AAC was analyzed as an outcome variable with 3 categories of severity, significant dose-response relations between the severity of AAC and alcohol consumption were observed, with those who drank frequently (>5/week) or excessively having more serious AAC (P for trend=0.03 and 0.02, respectively). No significant association was found in women as few drank excessively. CONCLUSION: The presence and severity of AAC were associated with quantity or frequency of alcohol consumption in a dose-response pattern, suggesting that alcohol drinking, even when moderate, has no benefit for AAC. Excessive drinking increased the risk of AAC by 50% compared to never drinkers. |
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Authors:
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Chao Qiang Jiang; Lin Xu; Tai Hing Lam; G Neil Thomas; Wei Sen Zhang; Kar Keung Cheng; C Mary Schooling |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2011-8-1 |
Journal Detail:
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Title: International journal of cardiology Volume: - ISSN: 1874-1754 ISO Abbreviation: - Publication Date: 2011 Aug |
Date Detail:
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Created Date: 2011-8-4 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8200291 Medline TA: Int J Cardiol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Copyright Information:
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Copyright © 2011 Elsevier Ireland Ltd. All rights reserved. |
Affiliation:
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Guangzhou No. 12 Hospital, Guangzhou 510620, China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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