Document Detail


Alcohol abuse in pregnant women: effects on the fetus and newborn, mode of action and maternal treatment.
MedLine Citation:
PMID:  20616979     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Offspring of mothers using ethanol during pregnancy are known to suffer from developmental delays and/or a variety of behavioral changes. Ethanol, may affect the developing fetus in a dose dependent manner. With very high repetitive doses there is a 6-10% chance of the fetus developing the fetal alcoholic syndrome manifested by prenatal and postnatal growth deficiency, specific craniofacial dysmorphic features, mental retardation, behavioral changes and a variety of major anomalies. With lower repetitive doses there is a risk of "alcoholic effects" mainly manifested by slight intellectual impairment, growth disturbances and behavioral changes. Binge drinking may impose some danger of slight intellectual deficiency. It is advised to offer maternal abstinence programs prior to pregnancy, but they may also be initiated during pregnancy with accompanying close medical care. The long term intellectual outcome of children born to ethanol dependent mothers is influenced to a large extent by the environment in which the exposed child is raised.
Authors:
Asher Ornoy; Zivanit Ergaz
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Publication Detail:
Type:  Journal Article; Review     Date:  2010-01-27
Journal Detail:
Title:  International journal of environmental research and public health     Volume:  7     ISSN:  1660-4601     ISO Abbreviation:  Int J Environ Res Public Health     Publication Date:  2010 Feb 
Date Detail:
Created Date:  2010-07-09     Completed Date:  2010-10-05     Revised Date:  2013-05-29    
Medline Journal Info:
Nlm Unique ID:  101238455     Medline TA:  Int J Environ Res Public Health     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  364-79     Citation Subset:  IM    
Affiliation:
Laboratory of Teratology, The Institute of Medical Research Israel Canada, Hadassah Medical School and Hospital, The Hebrew University of Jerusalem, Ein Kerem, P.O. Box 12271, Jerusalem, 91120, Israel.
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MeSH Terms
Descriptor/Qualifier:
Alcoholism / complications*,  genetics,  therapy
Female
Fetal Alcohol Syndrome* / genetics
Genetic Predisposition to Disease
Humans
Infant, Newborn
Maternal Exposure*
Pregnancy
Pregnancy Complications*
Comments/Corrections

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