Document Detail

Alcohol, IgE and allergy.
MedLine Citation:
PMID:  15511713     Owner:  NLM     Status:  MEDLINE    
Alcoholic drinks are involved in a variety of hypersensitivity reactions. These include flushing syndrome, anaphylactoid reactions (urticaria/angioedema and even shock), as well as the triggering of asthma, food allergy or exercise-induced anaphylaxis in susceptible subjects. In addition, there is increasing evidence that alcohol intake may play a role as a promoter of the development of immunoglobulin-E (IgE)-mediated hypersensitivity to different allergens. It seems clear that alcohol intake (alcohol abuse and even moderate alcohol consumption) is associated with increased total serum IgE levels. Similarly, alcohol intake may be associated with allergic (IgE-mediated) sensitization to environmental allergens. The clinical significance of these facts is probably moderate. The mechanisms by which alcohol can influence IgE responses are not entirely known, but further developments in this area could increase the understanding of both allergic diseases and alcohol-induced alterations in the immune system.
Arturo Gonzalez-Quintela; Carmen Vidal; Francisco Gude
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Addiction biology     Volume:  9     ISSN:  1355-6215     ISO Abbreviation:  Addict Biol     Publication Date:    2004 Sep-Dec
Date Detail:
Created Date:  2004-10-29     Completed Date:  2005-02-23     Revised Date:  2007-03-27    
Medline Journal Info:
Nlm Unique ID:  9604935     Medline TA:  Addict Biol     Country:  England    
Other Details:
Languages:  eng     Pagination:  195-204     Citation Subset:  IM    
Department of Internal Medicine, Hospital Clinico Universitario, 15706 Santiago de Compostela, Spain.
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MeSH Terms
Alcohol Drinking / immunology
Alcoholic Beverages / adverse effects*
Alcoholism / immunology*
Allergens / immunology
Hypersensitivity / etiology*,  immunology
Immunoglobulin E / blood*
Risk Factors
Reg. No./Substance:
0/Allergens; 37341-29-0/Immunoglobulin E

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