Document Detail


Alcohol Consumption Decreases the Protection Efficiency of the Antioxidant Network and Increases the Risk of Sunburn in Human Skin.
MedLine Citation:
PMID:  23147451     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
In recent years, epidemiological data has demonstrated that alcohol consumption is a risk factor for sunburn, melanoma and nonmelanoma skin cancer. We hypothesized that if the concentration of the antioxidants in the skin has already decreased due to alcohol consumption, then an adequate neutralization of the free radicals induced by ultraviolet light cannot be performed. Based on this hypothesis, we determined the carotenoid concentration in the skin and the minimal erythema dose (MED) of 6 male human volunteers before and after consumption of alcohol or alcohol and orange juice combined. The results showed a significant decrease in the carotenoid concentration in the skin and the MED after alcohol consumption, but no significant decrease after a combined intake of alcohol and orange juice.
Authors:
M E Darvin; W Sterry; J Lademann; A Patzelt
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-11-07
Journal Detail:
Title:  Skin pharmacology and physiology     Volume:  26     ISSN:  1660-5535     ISO Abbreviation:  Skin Pharmacol Physiol     Publication Date:  2012 Nov 
Date Detail:
Created Date:  2012-11-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101188418     Medline TA:  Skin Pharmacol Physiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  45-51     Citation Subset:  -    
Copyright Information:
Copyright © 2012 S. Karger AG, Basel.
Affiliation:
Center of Experimental and Applied Cutaneous Physiology, Department of Dermatology, Venerology and Allergology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
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