| Albumin excretory rate in normal and hypertensive pregnancy. | |
| | |
MedLine Citation:
|
PMID: 8156734 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
1. The purpose of this study was to determine whether the 24 h urinary albumin excretory rate was increased in the third trimester of normal pregnancy or in pregnant women with hypertension who had 24 h urinary total protein excretion within the normal range. 2. Twenty-four hour urinary creatinine and albumin excretions were determined prospectively in 26 non-pregnant and 115 pregnant women in their third trimester (40 in normal pregnancy, 38 with mild pre-eclampsia, 20 with severe pre-eclampsia, 17 with essential hypertension) in whom urinary total protein excretion was normal. Both the urinary albumin excretion rate and the urinary albumin/creatinine ratio were compared among the groups. The clearance of albumin relative to that of creatinine was also calculated in the hypertensive women and in 14 of the non-pregnant women and nine of the normal pregnant women. 3. The twenty-four hour urinary albumin excretion rate was similar in non-pregnant [8(5-10) mg/day; median (interquartile range)] and normal pregnant [7(6-10) mg/day] women. Women with essential hypertension [6(4-16) mg/day] and mild pre-eclampsia [7(4-10) mg/day] had a urinary albumin excretion rate similar to that of normal pregnant women. Women with severe pre-eclampsia had an urinary albumin excretion rate increased [13(7-32) mg/day] compared with other groups (P < 0.05). The clearance of albumin relative to that of creatinine was elevated significantly only in women with severe pre-eclampsia compared with normal pregnant women (0.00054 versus 0.00012; P < 0.05). Blood pressures were similar among all hypertensive groups.(ABSTRACT TRUNCATED AT 250 WORDS) |
| | |
Authors:
|
M A Brown; M X Wang; M L Buddle; M A Carlton; G M Cario; V C Zammit; J A Whitworth |
Related Documents
:
|
22150404 - Variability in muscle activity and wrist motion measurements among workers performing n... 20981214 - What are the risk factors for acute suppurative cholangitis caused by common bile duct ... 20833024 - Normal urine output after elective caesarean section: an observational study. 21737124 - Plasma factor vii-activating protease is increased by oral contraceptives and induces f... 17433084 - Simultaneous measurement of pelvic floor muscle activity and vaginal blood flow: a pilo... 22966214 - Both acute and chronic placental inflammation are overrepresented in term stillbirths: ... |
Publication Detail:
|
Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Clinical science (London, England : 1979) Volume: 86 ISSN: 0143-5221 ISO Abbreviation: Clin. Sci. Publication Date: 1994 Mar |
Date Detail:
|
Created Date: 1994-05-19 Completed Date: 1994-05-19 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 7905731 Medline TA: Clin Sci (Lond) Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 251-5 Citation Subset: IM |
Affiliation:
|
Department of Renal Medicine, St George Hospital, Sydney, Australia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Albuminuria / complications* Creatinine / urine Female Humans Hypertension / urine* Pre-Eclampsia / urine Pregnancy Pregnancy Complications, Cardiovascular / urine* Pregnancy Trimester, Third Prospective Studies |
| Chemical | |
Reg. No./Substance:
|
60-27-5/Creatinine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Involvement of nitric oxide in the vasodilatory response to parathyroid hormone-related peptide in t...
Next Document: Contractile dysfunction in the diabetic-rat heart is an intrinsic abnormality of the cardiac myocyte...