Document Detail

Akathisia masked by hypokinesia.
MedLine Citation:
PMID:  10958265     Owner:  NLM     Status:  MEDLINE    
Here, we will discuss the concept of subjective akathisia and present a patient case. Our patient was suffering from neuroleptic-induced hypokinesia and akathisia at the same time. The typical motor manifestations of akathisia were masked by hypokinesia, which made the diagnosis difficult. However, the subjective symptoms of akathisia were evident and distressing. Although not observable to bare eye, the pathognomonic pattern of motor activity detected in akathisia was demonstrated by actometric recording. Changing the conventional neuroleptic to an atypical one brought relief to the subjective symptoms of akathisia and hypokinesia, while the motor activity was clearly diminished in actometric recording. Actometric recording may be useful in diagnosing akathisia masked by hypokinesia, but the typical subjective symptoms of akathisia should not be ignored, even when actometry is not available to demonstrate the missing motor component of akathisia. Not only akathisia defined by DSM-IV but also subjective akathisia should be adequately treated to relieve the subjective distress, and to diminish the unfavorable effects on psychotic symptoms, behavior, and drug compliance.
K Tuisku; H Lauerma; M M Holi; T Honkonen; R Rimon
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Pharmacopsychiatry     Volume:  33     ISSN:  0176-3679     ISO Abbreviation:  Pharmacopsychiatry     Publication Date:  2000 Jul 
Date Detail:
Created Date:  2000-12-14     Completed Date:  2000-12-14     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  8402938     Medline TA:  Pharmacopsychiatry     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  147-9     Citation Subset:  IM    
Department of Psychiatry, University of Helsinki, Finland.
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MeSH Terms
Akathisia, Drug-Induced / complications*,  diagnosis*
Antipsychotic Agents / adverse effects*
Anxiety Disorders / drug therapy*
Clopenthixol / adverse effects*
Diazepam / therapeutic use*
Hypokinesia / chemically induced*,  complications*
Motor Activity
Reg. No./Substance:
0/Antipsychotic Agents; 439-14-5/Diazepam; 982-24-1/Clopenthixol

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