| Airway obstruction in asthmatic and healthy individuals: inspiratory and expiratory thin-section CT findings. | |
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MedLine Citation:
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PMID: 9114089 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To determine differences in computed tomographic (CT) findings in asthmatic and healthy individuals and to correlate the findings with severity of airway obstruction. MATERIALS AND METHODS: Thirty-nine asthmatic patients and 14 healthy subjects were prospectively evaluated with thin-section CT. Inspiratory CT scans were subjectively evaluated for presence of bronchial wall thickening, bronchial dilatation, and mosaic lung attenuation; expiratory scans were subjectively evaluated for presence of air trapping. Objective measurement of bronchoarterial-diameter ratio was performed on inspiratory scans. CT findings were compared with pulmonary function test results. RESULTS: Bronchial wall thickening, severe air trapping, and reduced bronchoarterial-diameter ratio were observed more commonly in asthmatic patients than in healthy subjects. Bronchial wall thickening was more prevalent among patients with severe airflow obstruction (10 of 12 readings [83%]) than in patients with normal airflow (15 of 40 readings [38%]) or mild obstruction (nine of 26 readings [35%]). Other subjectively determined CT findings did not correlate with pulmonary function test results. The mean bronchoarterial-diameter ratios +/- 1 standard deviation were 0.65 +/- 0.16 in healthy subjects and 0.60 +/- 0.16, 0.60 +/- 0.18, and 0.48 +/- 0.11 in patients with normal airflow and mild and severe obstruction, respectively. CONCLUSION: Thin-section CT is of limited value in distinguishing asthmatic patients with normal airflow or mild airflow obstruction from healthy subjects. |
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Authors:
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C S Park; N L Müller; S A Worthy; J S Kim; N Awadh; M Fitzgerald |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Radiology Volume: 203 ISSN: 0033-8419 ISO Abbreviation: Radiology Publication Date: 1997 May |
Date Detail:
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Created Date: 1997-05-13 Completed Date: 1997-05-13 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0401260 Medline TA: Radiology Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 361-7 Citation Subset: AIM; IM |
Affiliation:
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Department of Radiology, University of British Columbia and Vancouver Hospital and Health Sciences Centre, Canada. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Airway Obstruction / radiography* Asthma / complications, physiopathology, radiography* Female Humans Male Middle Aged Prospective Studies Respiration / physiology* Respiratory Function Tests Tomography, X-Ray Computed* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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