| Airway injury during high-level exercise. | |
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MedLine Citation:
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PMID: 22247295 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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Airway epithelial cells act as a physical barrier against environmental toxins and injury, and modulate inflammation and the immune response. As such, maintenance of their integrity is critical. Evidence is accumulating to suggest that exercise can cause injury to the airway epithelium. This seems the case particularly for competitive athletes performing high-level exercise, or when exercise takes place in extreme environmental conditions such as in cold dry air or in polluted air. Dehydration of the small airways and increased forces exerted on to the airway surface during severe hyperpnoea are thought to be key factors in determining the occurrence of injury of the airway epithelium. The injury-repair process of the airway epithelium may contribute to the development of the bronchial hyper-responsiveness that is documented in many elite athletes. |
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Authors:
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Pascale Kippelen; Sandra D Anderson |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-1-12 |
Journal Detail:
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Title: British journal of sports medicine Volume: - ISSN: 1473-0480 ISO Abbreviation: - Publication Date: 2012 Jan |
Date Detail:
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Created Date: 2012-1-16 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0432520 Medline TA: Br J Sports Med Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Centre for Sports Medicine & Human Performance, Brunel University, Uxbridge, UK. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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