| Airway closure and fluid filtration in the lung. | |
| | |
MedLine Citation:
|
PMID: 465266 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
We have investigated the effect of airway closure on fluid balance in the isolated, perfused rabbit lung in which the alveolar, pleural and vascular pressures could be regulated independently. The rate of filtration into the interstitial space was monitored by continuous weighing. A reduction in pleural pressure of 0.5 kPa with open airways increased fluid filtration by 0.11 g min-1. Reduction in pleural pressure of 0.5 kPa with the main airways closed reduced the alveolar pressure by 0.4 kPa and increased fluid filtration by 0.86 g minp1. We concluded that the pleural pressure is transmitted poorly to the alveolar interstitial space in the normal lung with open airways. However, airway closure allows the pleural pressure to be transmitted almost completely to this interstitium, with interstitial oedema as a possible consequence. |
| | |
Authors:
|
N Smith-Erichsen; G Bø |
Related Documents
:
|
12503716 - Components of respiratory resistance monitored in mechanically ventilated patients. 19703816 - Children with respiratory distress treated with high-flow nasal cannula. 3693166 - Effects of lung inflation on nasal airway resistance in the anesthetized rat. 15311146 - Effect of continuous positive airway pressure on ambulatory blood pressure in patients ... 9797186 - Psychobehavioral factors involved in the isolated office hypertension: comparison with ... 23112586 - Fabrication of high sensitivity carbon microcoil pressure sensors. |
Publication Detail:
|
Type: In Vitro; Journal Article |
Journal Detail:
|
Title: British journal of anaesthesia Volume: 51 ISSN: 0007-0912 ISO Abbreviation: Br J Anaesth Publication Date: 1979 Jun |
Date Detail:
|
Created Date: 1979-10-24 Completed Date: 1979-10-24 Revised Date: 2006-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 0372541 Medline TA: Br J Anaesth Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 475-9 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Airway Obstruction
/
complications,
physiopathology* Animals Extracellular Space / physiology* Female Filtration Lung / physiopathology* Male Perfusion Pulmonary Edema / etiology Rabbits |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Small endotracheal tubes: ventilator and intratracheal pressures during controlled ventilation.
Next Document: Effect of i.v. administration of lignocaine and tetrodotoxin on sensory units in the tooth of the ca...