Document Detail

Airway anomalies in patients with congenital diaphragmatic hernia.
MedLine Citation:
PMID:  11083423     Owner:  NLM     Status:  MEDLINE    
PURPOSE: Congenital diaphragmatic hernias (CDH) sometimes are associated with airway anomalies such as congenital stenosis, abnormal branching of the bronchi, and pulmonary hypoplasia. The incidence of these associated airway anomalies has not been reported previously. METHODS: Bronchoscopy was performed in all neonates with CDH from 1987 to 1999. In addition to anatomic anomalies, bronchial hypoplasia was defined as narrowing and shortening of the bronchi at bronchoscopy. RESULTS: Anatomic anomalies were identified in 7 of 39 patients with CDH: 1 had congenital tracheal stenosis with pulmonary artery sling, 1 had a defect of the right upper lobe bronchus, 2 had a tracheal bronchus, and 3 had a trifurcated trachea. Bronchial hypoplasia on the affected side was identified in 15 patients and was seen in all patients with anatomic anomalies of the tracheobronchial tree except the 2 with tracheal bronchus. After excluding 5 patients with severe associated anomalies, 6 of 14 patients with an abnormal tracheobronchial tree died, whereas 1 of 20 patients without airway abnormalities died. CONCLUSIONS: Anatomic anomalies of the tracheobronchial tree and bronchial hypoplasia on the affected side were identified in 17.9% and 38.4% of patients with CDH, respectively. CDH patients who exhibited these abnormalities showed a poor outcome.
K Nose; S Kamata; T Sawai; Y Tazuke; N Usui; H Kawahara; A Okada
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Journal of pediatric surgery     Volume:  35     ISSN:  0022-3468     ISO Abbreviation:  J. Pediatr. Surg.     Publication Date:  2000 Nov 
Date Detail:
Created Date:  2001-12-07     Completed Date:  2002-01-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0052631     Medline TA:  J Pediatr Surg     Country:  United States    
Other Details:
Languages:  eng     Pagination:  1562-5     Citation Subset:  IM    
Department of Pediatric Surgery, Osaka University Medical School, Japan.
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MeSH Terms
Bronchial Diseases / congenital,  epidemiology*
Bronchoscopy / methods
Hernia, Diaphragmatic / congenital*,  epidemiology*,  surgery
Infant, Newborn
Lung / abnormalities*
Lung Diseases / diagnosis,  epidemiology*
Risk Assessment
Survival Analysis
Trachea / abnormalities*

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