Document Detail

Airway Pressure Release Ventilation: What Do We Know?
MedLine Citation:
PMID:  21762559     Owner:  NLM     Status:  Publisher    
Airway Pressure Release Ventilation (APRV) is inverse ratio pressure controlled intermittent mandatory ventilation. It is based on the principle of open lung approach. It has many purported advantages over conventional ventilation including alveolar recruitment, improved oxygenation, preservation of spontaneous breathing, improved hemodynamics, and potential lung protective effects. It has many claimed disadvantages related to risks of volutrauma, increased work of breathing, and increased energy expenditure related to spontaneous breathing. APRV is used mainly as a rescue therapy for the difficult to oxygenate patients with Adult Respiratory Distress Syndrome (ARDS). There is confusion regarding this mode of ventilation due to the different terminology used in the literature. APRV setting include the "P High", "T high", "P Low", and "T Low". Physicians and respiratory therapists should be aware of the different ways and the rationales for setting these variables on the ventilators. Also, they should be familiar with the differences between APRV, BIPAP, and other conventional and non-conventional modes of ventilation. There is no solid proof that APRV improves mortality; however, there are ongoing studies that may reveal further information about this mode of ventilation. This article reviews the different methods proposed for APRV settings, and summarizes the different studies comparing APRV and BIPAP, and the potential benefits and pitfalls for APRV.
Ehab G Daoud; Hany L Farag; Robert L Chatburn
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-7-12
Journal Detail:
Title:  Respiratory care     Volume:  -     ISSN:  0020-1324     ISO Abbreviation:  -     Publication Date:  2011 Jul 
Date Detail:
Created Date:  2011-7-18     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7510357     Medline TA:  Respir Care     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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