Document Detail

Airflow velocities in the airways during expiration on different end-expiratory lung volumes: computational study.
MedLine Citation:
PMID:  17946318     Owner:  NLM     Status:  MEDLINE    
We used our computational model of the respiratory system which features non-linear variation of airway dimensions and airway-generation-based structure to show airflow velocities (cm/sec) during natural slow expiration on different end-expiratory lung volumes. Expiratory airflow rates at the mouth can be easily measured using a flow meter. However, because there is no practical non-invasive method that is currently available to measure airflow velocity in the airways, the airflow velocities in airway generations 0 approximately 16 were studied using the computational model. An airflow velocity is given by an airflow rate (ml/sec)+a cross sectional area (cm(2)). The cross sectional areas vary depending on inflation and deflation of a lung during respiration, and thus, knowing expiratory airflow rates at the mouth does not go far along the way to find out airflow velocities in the airways. In this study, we first predicted variation of expiratory airflow rates on six different end-expiratory lung volumes using a concept of a time constant, a product of lung compliance and airway resistance, and computational simulation. Then airflow velocities during expiration on the six end-expiratory lung volumes were computed and compared at the conducting airways, airway generations 0 approximately 16.
Kiwon Sohn
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference     Volume:  1     ISSN:  1557-170X     ISO Abbreviation:  Conf Proc IEEE Eng Med Biol Soc     Publication Date:  2006  
Date Detail:
Created Date:  2007-10-23     Completed Date:  2008-03-10     Revised Date:  2014-08-21    
Medline Journal Info:
Nlm Unique ID:  101243413     Medline TA:  Conf Proc IEEE Eng Med Biol Soc     Country:  United States    
Other Details:
Languages:  eng     Pagination:  5599-602     Citation Subset:  IM    
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MeSH Terms
Airway Resistance
Computer Simulation
Equipment Design
Forced Expiratory Flow Rates
Lung / pathology*
Lung Compliance
Models, Theoretical
Pulmonary Ventilation
Respiratory System*
Tidal Volume

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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