Document Detail


Airborne particle exposure and extrinsic skin aging.
MedLine Citation:
PMID:  20664556     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
For decades, extrinsic skin aging has been known to result from chronic exposure to solar radiation and, more recently, to tobacco smoke. In this study, we have assessed the influence of air pollution on skin aging in 400 Caucasian women aged 70-80 years. Skin aging was clinically assessed by means of SCINEXA (score of intrinsic and extrinsic skin aging), a validated skin aging score. Traffic-related exposure at the place of residence was determined by traffic particle emissions and by estimation of soot in fine dust. Exposure to background particle concentration was determined by measurements of ambient particles at fixed monitoring sites. The impact of air pollution on skin aging was analyzed by linear and logistic regression and adjusted for potential confounding variables. Air pollution exposure was significantly correlated to extrinsic skin aging signs, in particular to pigment spots and less pronounced to wrinkles. An increase in soot (per 0.5 × 10(-5) per m) and particles from traffic (per 475  kg per year and square km) was associated with 20% more pigment spots on forehead and cheeks. Background particle pollution, which was measured in low residential areas of the cities without busy traffic and therefore is not directly attributable to traffic but rather to other sources of particles, was also positively correlated to pigment spots on face. These results indicate that particle pollution might influence skin aging as well.
Authors:
Andrea Vierkötter; Tamara Schikowski; Ulrich Ranft; Dorothea Sugiri; Mary Matsui; Ursula Krämer; Jean Krutmann
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-07-22
Journal Detail:
Title:  The Journal of investigative dermatology     Volume:  130     ISSN:  1523-1747     ISO Abbreviation:  J. Invest. Dermatol.     Publication Date:  2010 Dec 
Date Detail:
Created Date:  2010-11-11     Completed Date:  2010-12-17     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0426720     Medline TA:  J Invest Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2719-26     Citation Subset:  IM    
Affiliation:
Institut für umweltmedizinische Forschung an der Heinrich-Heine-Universität Düsseldorf gGmbH, Düsseldorf, Germany.
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MeSH Terms
Descriptor/Qualifier:
Aged
Aged, 80 and over
Air Pollutants / adverse effects*
Environmental Exposure / adverse effects
European Continental Ancestry Group / statistics & numerical data*
Female
Germany / epidemiology
Humans
Oxidative Stress / physiology
Rural Population / statistics & numerical data
Skin Aging* / ethnology,  pathology,  physiology
Soot / adverse effects*
Urban Population / statistics & numerical data
Vehicle Emissions*
Chemical
Reg. No./Substance:
0/Air Pollutants; 0/Soot; 0/Vehicle Emissions
Comments/Corrections
Comment In:
J Invest Dermatol. 2010 Dec;130(12):2696   [PMID:  21068731 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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