| Air pollution and lung cancer mortality in Harris County, Texas, 1979-1981. | |
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MedLine Citation:
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PMID: 3421235 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Elevated lung cancer mortality rates in Harris County, Texas compared with other US counties and previously published reports that suggested a causal relation between air pollution and lung cancer in Houston prompted this ecologic analysis. A weighted regression analysis was used to examine the air pollution-lung cancer mortality relation for white males in Harris County, Texas, 1979-1981. The regression model included the following census tract-specific characteristics: median age for white males, two social and demographic factors not strongly correlated with pollution (family life cycle and migration), an age-dependent smoking index, and a pollution measure based on total suspended particulates. This model indicated a statistically significant contribution of the pollution measure in explaining the intracounty variation in lung cancer mortality rates. The relation between air pollution and lung cancer mortality, however, appeared to be highly dependent on which social and demographic factors were selected for inclusion in the analysis. Air pollution was not demonstrated to be a strong determinant of lung cancer mortality in this study in that the presence of air pollution accounted for less than 5% of the total variation in intraurban lung cancer mortality. In addition, the interpretation of geographic analysis must be guarded due to the introduction of potential bias due to aggregation. The hypothesis that air pollution is contributory to lung cancer cannot be tested until other, stronger individual risk factors for lung cancer can be better measured and controlled in studies of this association. |
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Authors:
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P A Buffler; S P Cooper; S Stinnett; C Contant; S Shirts; R J Hardy; V Agu; B Gehan; K Burau |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S. |
Journal Detail:
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Title: American journal of epidemiology Volume: 128 ISSN: 0002-9262 ISO Abbreviation: Am. J. Epidemiol. Publication Date: 1988 Oct |
Date Detail:
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Created Date: 1988-10-18 Completed Date: 1988-10-18 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7910653 Medline TA: Am J Epidemiol Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 683-99 Citation Subset: IM |
Affiliation:
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Epidemiology Research Unit, University of Texas Health Science Center, Houston, School of Public Health 77225. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Aged Air Pollutants / adverse effects* Epidemiologic Methods Family Humans Lung Neoplasms / ethnology, etiology, mortality* Male Middle Aged Smoking / adverse effects Socioeconomic Factors Texas |
| Chemical | |
Reg. No./Substance:
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0/Air Pollutants |
| Comments/Corrections | |
Comment In:
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Am J Epidemiol. 1989 Nov;130(5):1065-6
[PMID:
2816894
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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