Document Detail


Air pollution and effects on reproductive-system functions globally with particular emphasis on the Brazilian population.
MedLine Citation:
PMID:  20336577     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
In recent years, numerous studies showed that exposure to environmental air pollutants affected reproductive functions and, in particular, produced adverse effects on pregnancy outcomes, fertility, and fetal health. Epidemiological studies demonstrated that exposure to ambient levels of air pollutants are associated with low birth weight, intrauterine growth retardation, prematurity, neonatal death, and decreased fertility in males. Experimental animal data supported these findings and indicated that female fertility was also disturbed. Although there are various mechanisms of action suggested to show the manner in which air pollutants alter pregnancy and the reproductive systems in both genders, further studies are needed to correlate causal relationships. This information would serve to better understand the underlying physiologic changes in the reproductive system induced by exposure to air pollutants and possibly establish a link between the dose and response of individual or mixture of air pollutants.
Authors:
Mariana Matera Veras; Elia Garcia Caldini; Marisa Dolhnikoff; Paulo Hil?rio Nascimento Saldiva
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Journal of toxicology and environmental health. Part B, Critical reviews     Volume:  13     ISSN:  1521-6950     ISO Abbreviation:  J Toxicol Environ Health B Crit Rev     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2010-03-25     Completed Date:  2010-04-09     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9802627     Medline TA:  J Toxicol Environ Health B Crit Rev     Country:  England    
Other Details:
Languages:  eng     Pagination:  1-15     Citation Subset:  IM    
Affiliation:
Laborat?rio de Polui??o Atmosf?rica Experimental (LIM05), Departamento de Patologia Faculdade de Medicina, Universidade de S?o Paulo, S?o Paulo.
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MeSH Terms
Descriptor/Qualifier:
Air Pollution / adverse effects*
Animals
Brazil / epidemiology
Environmental Exposure / adverse effects
Female
Fertility / drug effects
Humans
Infant Mortality
Infant, Low Birth Weight
Infant, Newborn
Infertility / chemically induced,  physiopathology
Male
Mice
Pregnancy
Premature Birth / chemically induced
Reproduction / drug effects*
World Health

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