| Agressive inflammatory myofibroblastic tumor of the liver with underlying schistosomiasis: a case report. | |
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MedLine Citation:
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PMID: 20806444 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Inflammatory myofibroblastic tumor (IMT) occurs infrequently in the liver. It is controversial whether it represents a low grade mesenchymal neoplasm or a reactive inflammatory lesion. Local recurrence and metastasis are rare and some tumors are associated with infectious agents. We report on a case of a large and partially resected IMT with local recurrence and diaphragm and kidney infiltration detected on routine surveillance two years later. Histologically, the tumor showed spindle cells without atypia, mitosis or necrotic areas in a myxoid and collagenized background with inflammatory cells. In the liver portal tracts, granulomatous lesions with viable eggs of Schistosoma mansoni were identified. Immunohistochemistry demonstrated spindle cells which were smooth-muscle actin and vimentin positive. In conclusion, this case points out that these histological patterns do not predict the aggressive biological behavior of the lesion. A reason for the recurrence and the infiltration may be incomplete tumor resection. Further investigation is necessary in order to better clarify an infectious cause in some IMTs. |
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Authors:
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Vera Lucia Pannain; Juliana Vial Passos; Ariovaldo Rocha Filho; Cristiane Villela-Nogueira; Adriana Caroli-Bottino |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: World journal of gastroenterology : WJG Volume: 16 ISSN: 1007-9327 ISO Abbreviation: World J. Gastroenterol. Publication Date: 2010 Sep |
Date Detail:
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Created Date: 2010-08-31 Completed Date: 2010-12-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100883448 Medline TA: World J Gastroenterol Country: China |
Other Details:
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Languages: eng Pagination: 4233-6 Citation Subset: IM |
Affiliation:
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Department of Pathology, Clementino Fraga Filho University Hospital, Federal University of Rio de Janeiro, 255 Rodolpho Paulo Rocco Av, 21941-590 Rio de Janeiro, Brazil. verapannain@hotmail.com |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Animals Female Humans Liver / parasitology Liver Neoplasms / diagnosis*, etiology*, surgery Neoplasm Recurrence, Local / diagnosis Neoplasms, Muscle Tissue / diagnosis*, etiology*, surgery Reoperation Schistosoma mansoni / isolation & purification Schistosomiasis / complications*, diagnosis* |
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