Document Detail

Agreement of two different spectral domain optical coherence tomography instruments for retinal nerve fiber layer measurements.
MedLine Citation:
PMID:  24982729     Owner:  NLM     Status:  PubMed-not-MEDLINE    
PURPOSE: To determine the agreement between Spectralis and Cirrus spectral domain optical coherence tomography (SD-OCT) measurements of peripapillary retinal nerve fiber layer (RNFL) thickness.
METHODS: Suspected or confirmed cases of glaucoma who met the inclusion criteria underwent peripapillary RNFL thickness measurement using both the Spectralis and Cirrus on the same day within a few minutes.
RESULTS: Measurements were performed on 103 eyes of 103 patients with mean age of 50.4±17.7 years. Mean RNFL thickness was 89.22±15.87 versus 84.54±13.68 µm using Spectralis and Cirrus, respectively. The difference between measurements and the average of paired measurements with the two devices showed a significant linear relationship. Bland-Altman plots demonstrated that Spectralis thickness values were systematically larger than that of Cirrus.
CONCLUSION: Spectralis OCT generates higher peripapillary RNFL thickness readings as compared to Cirrus OCT; this should be kept in mind when values obtained with different instruments are compared during follow-up.
Hooshang Faghihi; Fedra Hajizadeh; Hassan Hashemi; Mehdi Khabazkhoob
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of ophthalmic & vision research     Volume:  9     ISSN:  2008-2010     ISO Abbreviation:  J Ophthalmic Vis Res     Publication Date:  2014 Jan 
Date Detail:
Created Date:  2014-07-01     Completed Date:  2014-07-01     Revised Date:  2014-07-04    
Medline Journal Info:
Nlm Unique ID:  101497643     Medline TA:  J Ophthalmic Vis Res     Country:  Iran    
Other Details:
Languages:  eng     Pagination:  31-7     Citation Subset:  -    
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