Document Detail


Agreement between self-reported smoking and cotinine concentration in adolescents: a validation study in Brazil.
MedLine Citation:
PMID:  18710676     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
PURPOSE: To validate self-reported data on smoking in adolescents in comparison with cotinine concentration. METHODS: Two thousand two hundred nine seventh- and eighth-grade students from 32 public schools in Pelotas, Brazil. Adolescents were contacted twice--before and after an educational intervention--and samples of urine for cotinine analyses were taken. In this paper, only data from the baseline phase are presented. High-performance liquid chromatography was used for cotinine analysis. Two cutoff points for cotinine were used: 10 ng/mL and 30 ng/mL. Two self-reported smoking variables were used: at least one cigarette smoked in the previous 30 days; and daily smoking. RESULTS: The self-reported prevalence of smoking in the previous 30 days was 7.4%, and 0.9% of the adolescents reported to be daily smokers. Those who reported smoking in the previous 30 days presented mean cotinine values 10 times greater than those who reported to be nonsmokers. Using a cutoff of 10 ng/mL for cotinine, sensitivity of self-reported smoking was 16.3% (95% confidence interval [CI] 11.7; 20.9) and specificity was 93.6% (95% CI 92.8; 95.0). Using a cutoff of 30 ng/mL, sensitivity was 22.6% (95% CI 15.6; 29.6) and specificity was 93.7% (95% CI 92.6; 94.8). CONCLUSIONS: Self-reported smoking presents low agreement with cotinine concentration, suggesting that adolescents underestimate tobacco consumption.
Authors:
Maura C Malcon; Ana M B Menezes; Maria Cecilia F Assunção; Marilda B Neutzling; Pedro C Hallal
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Validation Studies     Date:  2008-04-25
Journal Detail:
Title:  The Journal of adolescent health : official publication of the Society for Adolescent Medicine     Volume:  43     ISSN:  1879-1972     ISO Abbreviation:  J Adolesc Health     Publication Date:  2008 Sep 
Date Detail:
Created Date:  2008-08-19     Completed Date:  2008-10-29     Revised Date:  2009-05-21    
Medline Journal Info:
Nlm Unique ID:  9102136     Medline TA:  J Adolesc Health     Country:  United States    
Other Details:
Languages:  eng     Pagination:  226-30     Citation Subset:  IM    
Affiliation:
Universidade Federal do Rio Grande do Sul, Brazil.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Behavior, Addictive
Brazil / epidemiology
Cotinine / analysis*,  urine
Female
Health Surveys
Humans
Male
Randomized Controlled Trials as Topic
Smoking / epidemiology*
Grant Support
ID/Acronym/Agency:
//Wellcome Trust
Chemical
Reg. No./Substance:
486-56-6/Cotinine
Comments/Corrections
Comment In:
J Adolesc Health. 2008 Sep;43(3):205-6   [PMID:  18710672 ]

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