| Agminated atypical (dysplastic) nevi: case report and review of the literature. | |
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MedLine Citation:
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PMID: 11453811 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Patients with the atypical mole syndrome have multiple dysplastic nevi that appear to be randomly distributed on certain preferred anatomical sites such as the upper back. These dysplastic nevi are thought to be acquired melanocytic nevi that begin appearing at puberty. To our knowledge, the presence of agminated atypical (dysplastic) nevi has not been reported. OBSERVATION: We describe a patient with the atypical mole syndrome who has more than 100 melanocytic nevi, many of which are clinically atypical and one of which proved to be a melanoma. Among his many melanocytic nevi is a cluster of approximately 50 nevi that are distributed in an area measuring 5 x 3 cm. The histopathologic features of these nevi are consistent with the diagnosis of "dysplastic nevus." CONCLUSIONS: To our knowledge, agminated atypical (dysplastic) nevi have not been described previously. The presence of agminated atypical (dysplastic) nevi in a patient with the atypical mole syndrome can be theorized to arise because of loss of heterozygosity. |
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Authors:
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A A Marghoob; R Blum; R Nossa; K J Busam; D Sachs; A Halpern |
Publication Detail:
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Type: Case Reports; Journal Article; Review |
Journal Detail:
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Title: Archives of dermatology Volume: 137 ISSN: 0003-987X ISO Abbreviation: Arch Dermatol Publication Date: 2001 Jul |
Date Detail:
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Created Date: 2001-07-16 Completed Date: 2001-07-26 Revised Date: 2008-03-17 |
Medline Journal Info:
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Nlm Unique ID: 0372433 Medline TA: Arch Dermatol Country: United States |
Other Details:
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Languages: eng Pagination: 917-20 Citation Subset: AIM; IM |
Affiliation:
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Dermatology Service, Memorial Sloan-Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Biopsy Diagnosis, Differential Dysplastic Nevus Syndrome / classification, pathology* Humans Male Terminology as Topic |
| Comments/Corrections | |
Comment In:
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Arch Dermatol. 2002 Jun;138(6):838
[PMID:
12056974
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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