| Aging in the nematode Caenorhabditis elegans: major biological and environmental factors influencing life span. | |
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MedLine Citation:
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PMID: 926867 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The free-living nematode Caenorhabditis elegans is an excellent experimental system for the study of aging. The present study identifies some of the major biological and environmental factors influencing life span as a prelude to more detailed genetic and biochemical analyses. Life span can be altered during any part of the life cycle by a change in either temperature or food concentration. Parental age and parental life span both have relatively small effects on progeny life span. The nematode accumulates fluorescent pigment resembling lipofuscin, and becomes less sensitive to ultra-violet radiation as it ages. |
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Authors:
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M R Klass |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Mechanisms of ageing and development Volume: 6 ISSN: 0047-6374 ISO Abbreviation: Mech. Ageing Dev. Publication Date: 1977 Nov-Dec |
Date Detail:
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Created Date: 1978-01-27 Completed Date: 1978-01-27 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0347227 Medline TA: Mech Ageing Dev Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 413-29 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aging* Lipofuscin / metabolism Nematoda / genetics, growth & development*, metabolism Reproduction Temperature Ultraviolet Rays |
| Chemical | |
Reg. No./Substance:
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0/Lipofuscin |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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