| Aging, exercise, and phytochemicals: promises and pitfalls. | |
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MedLine Citation:
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PMID: 15247065 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Phytochemicals are emerging comprehensive and versatile sources of antioxidants to be consumed to enhance the body's defenses against harmful reactive oxygen species generated endogenously or exogenously. Tocols, favonoids, and phenolic acids compose the majority of this class of antioxidants, although more complex compounds may also be involved, such as ginsenosides. In vitro and in vivo studies have demonstrated convincingly that dietary supplementation of phytochemicals has beneficial effects against certain types of pathogenesis, disease, cancer, and aging. There is evidence that these effects are related to the ability of phytochemicals to promote the antioxidant defense system and reduce oxidative stress and damage in the cell. However, due to their structural and chemical diversity and complexity, many of the benefits as well as potential adverse effects remain to be examined. |
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Authors:
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Li Li Ji; David M Peterson |
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Publication Detail:
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Type: Journal Article; Review |
Journal Detail:
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Title: Annals of the New York Academy of Sciences Volume: 1019 ISSN: 0077-8923 ISO Abbreviation: Ann. N. Y. Acad. Sci. Publication Date: 2004 Jun |
Date Detail:
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Created Date: 2004-07-12 Completed Date: 2004-08-20 Revised Date: 2005-11-16 |
Medline Journal Info:
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Nlm Unique ID: 7506858 Medline TA: Ann N Y Acad Sci Country: United States |
Other Details:
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Languages: eng Pagination: 453-61 Citation Subset: IM |
Affiliation:
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Department of Kinesiology and Nutritional Sciences, University of Wisconsin-Madison, Madison, Wisconsin 53706, USA. ji@education.wisc.edu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aging* Animals Antioxidants / pharmacology* Blotting, Western Dietary Supplements* Female Free Radicals Oxidants / metabolism Oxidative Stress* Panax Physical Conditioning, Animal Rats Rats, Sprague-Dawley Reactive Oxygen Species Time Factors |
| Chemical | |
Reg. No./Substance:
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0/Antioxidants; 0/Free Radicals; 0/Oxidants; 0/Reactive Oxygen Species |
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