Document Detail

Aging and the effect of increased after-load on left ventricular contractile state.
MedLine Citation:
PMID:  3386508     Owner:  NLM     Status:  MEDLINE    
Hemodynamic and contractile states were studied echocardiographically in 10 young (28 +/- 3 yr) and 10 elderly (67 +/- 4 yr) male subjects at rest and during upright isometric exercise which involved the hands, hips, legs, and lower back muscle groups (deadlift) at 30% of maximum voluntary contraction for 3 min. During deadlift, both groups showed similar and significant increases in blood pressure and heart rate, compared to the resting values. Ejection fraction at rest did not differ significantly between the two groups. During deadlift, it remained unchanged in the elderly white ejection fraction increased significantly in the younger subjects. No significant changes in left ventricular end-diastolic volume occurred in either group during deadlift. End-systolic volume remained unchanged in the elderly while it decreased significantly in the younger subjects. These data indicate that cardiovascular responses and contractile state in normal young men and normal exercise-trained elderly subjects were augmented during upright sub-maximal isometric deadlift exercise, utilizing large muscle mass. However, left ventricular contractility increased less in the elderly subjects compared to the younger subjects.
M Sagiv; E Goldhammer; E G Abinader; J Rudoy
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medicine and science in sports and exercise     Volume:  20     ISSN:  0195-9131     ISO Abbreviation:  Med Sci Sports Exerc     Publication Date:  1988 Jun 
Date Detail:
Created Date:  1988-08-08     Completed Date:  1988-08-08     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  8005433     Medline TA:  Med Sci Sports Exerc     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  281-4     Citation Subset:  IM; S    
Sports Medicine Department, Zinman College, Wingate Institute, Haifa, Israel.
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MeSH Terms
Aging / physiology*
Isometric Contraction*
Muscle Contraction*
Myocardial Contraction*
Ventricular Function*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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